BioengineeringbioRxivPreprint
Fed-batch production of antiviral OP7 chimera defective interfering influenza A particles
Wiebke Holste, Sascha Young Kupke, Claudius Seitz…·Holger Ziehr
This paper develops a fed-batch production process for OP7 chimera DIPs, achieving higher virus titers and bioactivity compared to batch production, with potential for GMP manufacturing.
DOI 10.64898/2026.09.30.755589