Author

Holly Gibbs

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Systems Biology· 1

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Organism:mouse· 1 Approach:statistical model· 1

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Alexander Mazein· 1 shared Guanghou Shui· 1 shared Jane Hillston· 1 shared Kevin Robertson· 1 shared Laurence Loewe· 1 shared Maria-Luisa Guerriero· 1 shared Markus Wenk· 1 shared Mathieu Blanc· 1 shared

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1 shared paperSystems Biology

Alexander Mazein

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1 paper

Recent·Most cited

Systems BiologyBiochimiePeer-reviewedMar 1, 2013

A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction

Steven Watterson, Maria-Luisa Guerriero, Mathieu Blanc…·Peter Ghazal

The paper models cholesterol biosynthesis pathway regulation, showing immune responses cause gradual flux reduction while statin-like treatments cause abrupt flux reduction, with immune regulation being more specific.

DOI 10.1016/j.biochi.2012.05.024

mousestatistical model

𝕏 PostBluesky