GeneticsbioRxivPreprint
Overcoming the "feast or famine" effect: improved interaction testing in genome-wide association studies
Huanlin Zhou, Mary Sara McPeek
This paper identifies a 'feast or famine' effect in genome-wide interaction studies that causes inconsistent type 1 error rates and proposes TINGA to correct for it, improving power and reliability.
DOI 10.1101/2024.02.13.580168