Pharmacology & ToxicologybioRxivPreprint
Spatial architecture of complex antibody formats dictates pharmacokinetics via FcRn-recycling
Stefan C Weise, Cordula Jany, Sabine Imhof-Jung…·Thomas E. Kraft
This study shows how antibody structure affects FcRn recycling and pharmacokinetics, finding that invertbody design reduces clearance by threefold.
DOI 10.64898/2026.11.02.763654