Pharmacology & ToxicologyeLifePeer-reviewed
Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction
Soo‐Yeon Hwang, Kyung‐Hwa Jeon, Hwa-Jong Lee…·Youngjoo Kwon
This study synthesizes and evaluates chalcone and pyrazoline derivatives as ELF3-MED23 PPI inhibitors, showing compound 10 effectively reduces HER2 levels and induces apoptosis in HER2-positive gastric cancer cells.
3 citations