Cell BiologybioRxivPreprint
Structure-guided design of novel orthosteric inhibitors of integrin αIIbβ3 that prevent thrombosis but preserve hemostasis
Brian D. Adair, José L. Alonso, Johannes van Agthoven…·M. Amin Arnaout
This study designs a novel orthosteric inhibitor of integrin αIIbβ3 that prevents thrombosis without impairing hemostasis, using structure-guided methods.
DOI 10.1101/509299