GenomicsNature MethodsPeer-reviewed
Accurate Identification of Active Transcriptional Regulatory Elements from Global Run-On and Sequencing Data
Charles G Danko, Stephanie L Hyland, Leighton J Core…·Adam Siepel
The paper introduces dREG, a machine-learning method to identify active transcriptional regulatory elements from GRO-seq data, showing strong enrichment for functional marks.
DOI 10.1038/nmeth.3329