MicrobiologybioRxiv
The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype
T. Barut, N. J. Halwe, A. Taddeo…·V. Thiel
This study shows the spike gene determines replication, pathogenicity, and immune evasion of SARS-CoV-2 Omicron-BA.1 compared to Delta in cell cultures and animal models.