Adipose deficiency and aberrant autophagy in a Drosophila model of MPS VII is corrected by pharmacological stimulators of mTOR
I. Basu, S. Bar, M. Prasad, R. Datta
This study identifies autophagy dysfunction and mTOR downregulation as causes of adipose deficiency in a Drosophila model of MPS VII, showing that mTOR stimulators can reverse these defects.
bioRxiv · Sep 5, 2021Cell Biology