M. Prasad

SiHDA9 interacts with SiHAT3.1 and SiHDA19 to repress dehydration responses through H3K9 deacetylation in foxtail millet

The paper identifies SiHDA9's role in repressing drought responses by deacetylating H3K9 on target genes in foxtail millet through interaction with SiHAT3.1 and SiHDA19.

Alcanivorax borkumensis Biofilms Enhance Oil Degradation By Interfacial Tubulation

A. borkumensis biofilms transition from thick to thin dendritic phenotypes to enhance oil consumption through interfacial tubulation and reduced interfacial tension.

Adipose deficiency and aberrant autophagy in a Drosophila model of MPS VII is corrected by pharmacological stimulators of mTOR

This study identifies autophagy dysfunction and mTOR downregulation as causes of adipose deficiency in a Drosophila model of MPS VII, showing that mTOR stimulators can reverse these defects.

MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer

This study shows that MEK1/2 inhibition temporarily improves the tumor immune microenvironment, enhancing immunotherapy effectiveness in head and neck cancer by reducing suppressive myeloid cells and boosting CD8+ T cell activity.

Elucidating biosynthetic pathway of piperine using comparative transcriptome analysis of leaves, root, and spike in Piper longum L.

The paper uses transcriptome analysis of P. longum leaves, roots, and spikes to identify gene families involved in piperine biosynthesis and validates gene expression with qRT-PCR.

Praja1 ubiquitin ligase facilitates degradation of polyglutamine proteins and suppresses polyglutamine-mediated toxicity

This study identifies Praja1 as a ubiquitin ligase that degrades polyglutamine proteins and reduces their toxicity in neurodegenerative diseases.

Grain number and genotype drive nitrogen-dependent yield response in the C4 model Setaria italica (L.) P. Beauv.

This study shows that nitrogen-dependent yield response in Setaria italica is driven by grain number and genotypes, with low N responsive genotypes showing greater transcriptional changes under varying nitrogen levels post-flowering.

Molecular characterization and differential expression reveal functional divergence of stress-responsive enzymes in C4 panicoid models, Setaria italica and Setaria viridis

The paper identifies and characterizes stress-responsive genes in C4 plants Setaria italica and S. viridis, highlighting key candidates for abiotic stress tolerance.

Designing of a mini-core that effectively represents 3004 diverse accessions of rice

The paper designs a mini-core of 520 rice accessions that effectively represents the genetic diversity of 3004 rice accessions, capturing SNPs, phenotypes, and geographical regions.

The AP-1 complex regulates AXL expression and determines sensitivity to PI3Kα inhibition in esophagus and head and neck squamous cell carcinoma

This study shows that AP-1 factors regulate AXL expression, which contributes to resistance to PI3Kα inhibition in ESCC and HNSCC, and that JNK inhibition combined with PI3Kα inhibition enhances anti-tumor effects.