Author

I. Bochkis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

A. Wu· 1 shared J. Linden· 1 shared L. Han· 1 shared M. A. Luse· 1 shared M. C. Lemke· 1 shared M. E. Granade· 1 shared S. R. Hargett· 1 shared T. E. Harris· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Wu

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2 papers

Recent·Most cited

Pioneer factor Foxa2 mediates chromatin conformation changes in ligand-dependent activation of nuclear receptor FXR

Y. Hao, L. Han, A. Wu, I. Bochkis

The paper shows Foxa2 enables chromatin conformation changes during FXR ligand activation in mouse livers, increasing long-range interactions and altering TADs and loops.

bioRxiv · Mar 6, 2023 · PreprintPharmacology & Toxicology

Feeding desensitizes A1 adenosine receptors in adipose through FOXO1-mediated transcriptional regulation

M. E. Granade, S. R. Hargett, M. C. Lemke, M. A. Luse, I. Bochkis, J. Linden, T. E. Harris

This study shows that feeding reduces A1R expression in adipose tissue via FOXO1-mediated transcription, impairing insulin suppression of lipolysis and glucose tolerance.

bioRxiv · Mar 4, 2022Physiology