Author

I. Boo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

H. E. Drummer· 4 shared E. S. J. Edwards· 3 shared G. E. Hartley· 3 shared M. C. van Zelm· 3 shared P. M. Hogarth· 3 shared R. E. O'Hehir· 3 shared S. J. Bornheimer· 3 shared H. A. Fryer· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersImmunology

H. E. Drummer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Third dose COVID-19 mRNA vaccine enhances IgG4 isotype switching and recognition of Omicron subvariants by memory B cells after mRNA but not adenovirus priming

G. E. Hartley, H. A. Fryer, P. A. Gill, I. Boo, S. J. Bornheimer, P. M. Hogarth, H. E. Drummer, R. E. O'Hehir, E. S. J. Edwards, M. C. van Zelm

This study shows that a third mRNA COVID-19 vaccine dose increases IgG4+ memory B cells and Omicron subvariant recognition, but only in those primed with mRNA, not adenovirus.

bioRxiv · Sep 15, 2023 · PreprintImmunology

COVID-19 adenoviral vector vaccination elicits a robust memory B cell response with the capacity to recognize Omicron BA.2 and BA.5 variants

H. A. Fryer, G. E. Hartley, E. S. J. Edwards, N. Varese, I. Boo, S. J. Bornheimer, P. M. Hogarth, H. E. Drummer, R. E. O'Hehir, M. C. van Zelm

This study compares memory B cell responses to ChAdOx1 and BNT162b2 vaccines, showing ChAdOx1 generates Bmem recognizing Omicron variants BA.2 and BA.5.

bioRxiv · Feb 28, 2023 · PreprintImmunology

Enhanced stability of the SARS CoV-2 spike glycoprotein trimer following modification of an alanine cavity in the protein core.

P. Poumbourios, C. Langer, I. Boo, T. Zakir, R. J. Center, A. Akerman, V. Milogiannakis, A. Aggarwal, S. G. Turville, H. E. Drummer

This paper modifies the SARS-CoV-2 spike protein to enhance thermal stability and neutralizing antibody response against ancestral and Delta variants, but reduced effectiveness against Omicron BA.1.

bioRxiv · Nov 8, 2022 · PreprintMicrobiology

Double-dose mRNA vaccination to SARS-CoV-2 progressively increases recognition of variants-of-concern by Spike RBD-specific memory B cells

G. E. Hartley, E. S. J. Edwards, N. Varese, I. Boo, P. M. Aui, S. J. Bornheimer, P. M. Hogarth, H. E. Drummer, R. E. O'Hehir, M. C. van Zelm

This study shows that a second dose of BNT162b2 vaccine increases the number and variant recognition ability of RBD-specific memory B cells.

bioRxiv · Aug 3, 2022 · PreprintImmunology