Author

A. Akerman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Organism:mouse· 1

Frequent Co-Authors

A. Aggarwal· 2 shared S. G. Turville· 2 shared V. Milogiannakis· 2 shared A. Cartaya· 1 shared A. D. Kelleher· 1 shared A. Khromykh· 1 shared A. Kindinger· 1 shared C. Esneau· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

A. Aggarwal

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by Collectrin-like domain of ACE2

A. Aggarwal, C. Fichter, V. Milogiannakis, T. Ison, M. Ruiz Silva, C. Esneau, N. Bartlett, L. Burrell, S. Patel, M. Churchill, T. Angelovich, R. Parry, J. D. Sng, G. G. Neely, C. L. Moreno, , S. G. Turville

The paper shows Omicron SARS-CoV-2 lineages rely on ACE2 without TMPRSS2 complexes for entry, due to changes in the ACE2 Collectrin-Like Domain affecting TMPRSS2 activation.

bioRxiv · Sep 22, 2023 · PreprintMicrobiology

Enhanced stability of the SARS CoV-2 spike glycoprotein trimer following modification of an alanine cavity in the protein core.

P. Poumbourios, C. Langer, I. Boo, T. Zakir, R. J. Center, A. Akerman, V. Milogiannakis, A. Aggarwal, S. G. Turville, H. E. Drummer

This paper modifies the SARS-CoV-2 spike protein to enhance thermal stability and neutralizing antibody response against ancestral and Delta variants, but reduced effectiveness against Omicron BA.1.

bioRxiv · Nov 8, 2022 · PreprintMicrobiology

Antioxidant Response Activating nanoParticles (ARAPas) localize to atherosclerotic plaque and locally activate the Nrf2 pathway

S. L. Maiocchi, A. Cartaya, S. Thai, A. Akerman, E. M. Bahnson

This study develops ARAPas, nanoparticles that target atherosclerotic plaque and activate the Nrf2 pathway, showing anti-inflammatory effects and increased Nrf2 target gene expression in mouse models.

bioRxiv · Sep 16, 2021Bioengineering