A new mechanism of posttranslational polyglutamylation regulates phase separation and signaling of the Wnt pathway protein Dishevelled.
M. Kravec, O. Sedo, J. Nedvedova…·V. Bryja
The paper identifies TTLL11-mediated polyglutamylation of DVL3 as a novel modification that regulates its phase separation and signaling in the non-canonical Wnt pathway.