Author

J. L. Ruas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

I. Cervenka· 2 shared J. C. Correia· 2 shared J. T. Lanner· 2 shared P. R. Jannig· 2 shared B. J. Wadsworth· 1 shared C. Asvestis· 1 shared C. Brombach· 1 shared C. Schweingruber· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersPhysiology

I. Cervenka

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Author profile →

3 papers

Recent·Most cited

A 2-Hydroxybutyrate-mediated feedback loop regulates muscular fatigue

B. J. Wadsworth, M. Leiwe, E. Minogue, P. P. Cunha, V. Engman, C. Brombach, C. Asvestis, S. K. Sah-Teli, E. Marklund, P. Karppinen, J. L. Ruas, H. Rundqvist, J. Lanner, R. S. Johnson

This study shows that 2-hydroxybutyrate (2HB) produced during exercise inhibits branched-chain aminotransferases, leading to metabolic changes that enhance oxidative capacity.

bioRxiv · Oct 16, 2023Physiology

Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration.

J. C. Correia, P. R. Jannig, M. L. Gosztyla, I. Cervenka, S. Ducommun, S. M. Praestholm, K. D. Dumont, Z. Liu, Q. Liang, D. Edsgard, O. Emanuelsson, P. Gregorevic, H. Westerblad, T. Venckunas, M. Brazaitis, , J. L. Ruas

This study identifies Zfp697 as a regulator of muscle regeneration and inflammation by mediating interferon gamma signaling and interacting with ncRNAs like miR-206.

bioRxiv · Jun 12, 2023 · PreprintPhysiology

Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity.

J. C. Correia, Y. Kelahmetoglu, P. R. Jannig, C. Schweingruber, D. Svaikovskaya, L. Zhengye, I. Cervenka, M. Oliveira, J. Nijssen, V. Martinez-Redondo, M. Stec, N. Khan, J. T. Lanner, S. Kleiner, E. Hedlund, J. L. Ruas

This paper shows that muscle-secreted neurturin (NRTN) couples muscle oxidative metabolism with slow motor neuron identity, improving exercise performance and motor coordination.

bioRxiv · Mar 31, 2021Physiology