I. Dasgupta

The ability of the LIMD1 and TRIP6 LIM domains to bind to f-actin under strain is critical for their tension dependent localization to adherens junctions and association with the Hippo pathway kinase LATS1.

This study shows that TRIP6 and LIMD1 bind to strained actin, enabling their localization to adherens junctions and interaction with LATS1, a key Hippo pathway kinase.

A geminivirus AC5 protein interacts with plant hormonal signalling and impacts plant defence

This study identifies AC5, a geminiviral protein, as interacting with the abscisic acid signaling pathway, impairing plant defense and facilitating virus propagation.

A theory of learning to infer

The paper proposes a theory explaining systematic deviations in human probabilistic inference by introducing a recognition model that adapts to query distribution.

TRIP6 inhibits the Hippo signaling pathway in response to tension at adherens junctions

This study identifies TRIP6 as a mechanotransduction component that inhibits Hippo signaling by blocking LATS1/2 activation in response to tension at adherens junctions.