Author

I. Head

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Microbiology· 1

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Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

C. L. Tooke· 1 shared C. Reding· 1 shared F. Edwards· 1 shared F. Hamilton· 1 shared J. M. Shaw· 1 shared J. Spencer· 1 shared K. J. Heesom· 1 shared M. B. Avison· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

C. L. Tooke

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1 paper

Recent·Most cited

Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics

P. Dulyayangkul, T. Beavis, W. W. Lee, R. Ardagh, F. Edwards, F. Hamilton, I. Head, K. J. Heesom, O. Mounsey, M. Murarik, C. Reding, N. Satapoomin, J. M. Shaw, Y. Takebayashi, C. L. Tooke, , M. B. Avison

The paper shows that gene cassettes in an integron, amplified by IS26, confer resistance to amikacin and piperacillin/tazobactam, often leaving meropenem as the last-resort antibiotic.

bioRxiv · Dec 2, 2023 · PreprintMicrobiology