Author

F. Edwards

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. E. Tijhuis· 1 shared A. Gervais· 1 shared A. Herbette· 1 shared A. Vincent-Salomon· 1 shared A. Y. Simon· 1 shared B. Lacroix· 1 shared C. L. Tooke· 1 shared C. Reding· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCell Biology

A. E. Tijhuis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics

P. Dulyayangkul, T. Beavis, W. W. Lee, R. Ardagh, F. Edwards, F. Hamilton, I. Head, K. J. Heesom, O. Mounsey, M. Murarik, C. Reding, N. Satapoomin, J. M. Shaw, Y. Takebayashi, C. L. Tooke, , M. B. Avison

The paper shows that gene cassettes in an integron, amplified by IS26, confer resistance to amikacin and piperacillin/tazobactam, often leaving meropenem as the last-resort antibiotic.

bioRxiv · Dec 2, 2023 · PreprintMicrobiology

Centrosome amplification primes for apoptosis and favors the response to chemotherapy in ovarian cancer beyond multipolar divisions

F. Edwards, G. Fantozzi, A. Y. Simon, J.-P. Morretton, A. Herbette, A. E. Tijhuis, R. Wardenaar, S. Foulane, S. Gemble, D. C. J. Spierings, F. Foijer, O. Mariani, A. Vincent-Salomon, S. Roman-Roman, X. Sastre-Garau, , R. Basto

The paper shows centrosome amplification in ovarian cancer cells primes them for apoptosis and improves chemotherapy response, independent of multipolar divisions and chromosome instability.

bioRxiv · Jul 28, 2023 · PreprintCell Biology

Synergistic stabilization of microtubules by BUB-1, HCP-1 and CLS- 2 controls meiotic spindle assembly in C. elegans oocytes

N. Macaisne, L. Bellutti, K. Laband, F. Edwards, L. Pitayu-Nugroho, A. Gervais, T. Ganeswaran, H. Geoffroy, G. Maton, J. C. Canman, B. Lacroix, J. Dumont

This study identifies the BHC module as essential for stabilizing microtubules during meiotic spindle assembly in C. elegans oocytes, ensuring accurate chromosome segregation.

bioRxiv · Aug 24, 2022 · PreprintCell Biology