Author

I. Kwee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Rinaldi· 3 shared F. Bertoni· 3 shared A. Cavalli· 2 shared A. J. Arribas· 2 shared A. Bruno· 1 shared A. M. Chiaravalli· 1 shared A. Ottolenghi· 1 shared A. Stathis· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

A. Rinaldi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PI3Kδ activation, IL6 over-expression, and CD37 loss cause resistance to the targeting of CD37-positive lymphomas with the antibody-drug conjugate naratuximab emtansine

A. J. Arribas, E. Gaudio, S. Napoli, C. J. Herbaux, C. Tarantelli, R. Bordone Pittau, L. Cascione, N. Munz, L. Aresu, J. Sgrignani, A. Rinaldi, I. Kwee, D. Rossi, A. Cavalli, E. Zucca, , F. Bertoni

This paper identifies two resistance mechanisms to the CD37-targeting ADC naratuximab emtansine in lymphoma cell lines and suggests combination therapies to overcome resistance.

bioRxiv · Nov 14, 2023 · PreprintCancer Biology

Myc controls IL-15-driven expansion and translational machinery of NK cells

H. J. Khameneh, N. Fonta, A. Zenobi, C. Niogret, P. Ventura, C. Guerra, I. Kwee, A. Rinaldi, M. Pecoraro, R. Geiger, A. Cavalli, F. Bertoni, E. E. Vivier, A. Trumpp, G. Guarda

This study shows that Myc is essential for NK cell development, expansion, and anticancer immunity by regulating translational machinery and IL-15 responses.

bioRxiv · Dec 20, 2022 · PreprintImmunology

IL-1α secreted by subcapsular sinus macrophages promotes melanoma metastasis in the sentinel lymph node by upregulating STAT3 signaling in the tumor.

T. Virgilio, J. Bordini, G. Sartori, I. Latino, D. Molina-Romero, C. Leoni, M. Akhmedov, A. Rinaldi, A. J. Arribas, D. Morone, S. M. S. Jafari, M. Bersudsky, A. Ottolenghi, I. Kwee, A. M. Chiaravalli, , S. F. Gonzalez

This study shows that IL-1α from subcapsular sinus macrophages promotes melanoma metastasis by enhancing STAT3 signaling in tumor cells, and blocking this pathway reduces metastasis.

bioRxiv · Oct 11, 2021 · PreprintImmunology