Author

I. M. Walsh

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Biochemistry· 1

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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A. Rodriguez· 1 shared I. F. Soto· 1 shared M. A. Bowman· 1 shared P. L. Clark· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperBiochemistry

A. Rodriguez

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1 paper

Recent·Most cited

BiochemistrybioRxivSep 13, 2019

Synonymous codon substitutions perturb co-translational protein folding in vivo and impair cell fitness

I. M. Walsh, M. A. Bowman, I. F. Soto…·P. L. Clark

This study shows that synonymous codon substitutions affect co-translational protein folding, leading to reduced cell fitness despite normal enzyme activity.

DOI 10.1073/pnas.1907126117

protein structureexperimental assay

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