PhysiologybioRxiv
Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver
K. Thapa, J. J. Kadiri, K. Saukkonen…·P. Rinne
This study shows that MC1-R in hepatocytes regulates cholesterol and bile acid metabolism, with its deficiency causing hypercholesterolemia and liver fibrosis.
DOI 10.7554/elife.84782