MicrobiologybioRxivPreprint
Dual inhibition of coronavirus Mpro and PLpro enzymes by phenothiazines and their antiviral activity
K. L. Forrestall, E. S. Pringle, D. Sands…·S. Darvesh
This paper identifies a phenothiazine urea derivative that inhibits both SARS-CoV-2 Mpro and PLpro proteases and shows broad antiviral activity against multiple human coronaviruses.
DOI 10.1101/2023.09.11.557219