Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer
M. A. Siddiqui, P. N. Gollavilli, V. Ramesh, B. Parma, A. Schwab, M. E. Vazakidou, R. Natesan, O. Saatci, I. Rapa, P. Bironzo, H. Schuhwerk, I. A. Asangani, O. Sahin, M. Volante, P. Ceppi
This study identifies thymidylate synthase (TS) as a driver of epithelial-to-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC), linking it to metastasis, chemotherapy resistance, and survival.
bioRxiv · Aug 13, 2020Cancer Biology