Metabolic breakdown of non-small cell lung cancers by mitochondrial HSPD1 targeting
B. Parma, V. Ramesh, P. N. Gollavilli, A. M. Siddiqui, L. Pinna, A. Schwab, S. Marshall, S. Zhang, C. Pilarsky, F. Napoli, M. Volante, S. Urbanczyk, D. Mielenz, H. D. Schroeder, M. Stemmler, , P. Ceppi
This study identifies HSPD1 as a therapeutic target in NSCLC, showing its disruption leads to metabolic breakdown and suppressed tumor growth.
bioRxiv · Mar 9, 2021Cancer Biology