V. Ramesh

A large-scale crowd-sourced annotated acoustic dataset of Indian fauna

The paper creates a crowd-sourced acoustic dataset of Indian fauna to support biodiversity monitoring and deep learning applications in conservation.

Pan-cancer analysis of pyrimidine metabolism reveals signaling pathways connections with chemoresistance role

The paper performs a pan-cancer analysis of pyrimidine metabolism, identifying pathway interactions linked to chemoresistance and showing that brequinar treatment reverses doxorubicin resistance.

Methionine availability influences essential H3K36me3 dynamics during cell differentiation

This study shows methionine availability affects H3K36me3 dynamics and myogenic differentiation in mouse cells through the histone methyltransferase SETD2.

Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis

This study shows that pathogenic mtDNA mutations in melanoma cells reduce metastasis by limiting circulation entry, despite promoting tumor growth.

Propionate reinforces epithelial identity and reduces aggressiveness of non-small cell lung carcinoma via chromatin remodelling

This study identifies propionate's role in reducing NSCLC aggressiveness by promoting epithelial identity through chromatin remodeling.

Is there an accurate and generalisable way to use soundscapes to monitor biodiversity?

This study investigates the generalisability of soundscape analysis for biodiversity monitoring and finds that acoustic features and machine learning models are inconsistent across datasets.

Metabolic breakdown of non-small cell lung cancers by mitochondrial HSPD1 targeting

This study identifies HSPD1 as a therapeutic target in NSCLC, showing its disruption leads to metabolic breakdown and suppressed tumor growth.

Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer

This study identifies thymidylate synthase (TS) as a driver of epithelial-to-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC), linking it to metastasis, chemotherapy resistance, and survival.

Modification of primary amines to higher order amines reduces in vivo hematological and immunotoxicity of cationic nanocarriers through TLR4 and complement pathways

This study shows modifying primary amines to higher order amines reduces toxicity of cationic nanocarriers by targeting TLR4 and complement pathways in vivo.