Author

I. Rostami

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Chiki· 1 shared D. Boudeffa· 1 shared H. A. Lashuel· 1 shared K. Rajasekhar· 1 shared L. A. Abriata· 1 shared L. Krapp· 1 shared M. Dal Peraro· 1 shared Z. Zhang· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

A. Chiki

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1 paper

Recent·Most cited

Investigating crosstalk among PTMs provides novel insight into the structural basis underlying the differential effects of Nt17 PTMs on mutant Httex1 aggregation

A. Chiki, Z. Zhang, K. Rajasekhar, L. A. Abriata, I. Rostami, L. Krapp, D. Boudeffa, M. Dal Peraro, H. A. Lashuel

This study investigates how PTMs in Nt17 of mutant Httex1 affect aggregation, showing that oxM8 delays aggregation and that combinations with AcK6 inhibit fibrillization, with structural insights from spectroscopy and simulations.

bioRxiv · Feb 21, 2021Biophysics