Author

L. Krapp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

M. Dal Peraro· 3 shared A. Chiki· 2 shared C. Cao· 1 shared D. Boudeffa· 1 shared F. Meireles· 1 shared H. A. Lashuel· 1 shared H. Lashuel· 1 shared I. Rostami· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiophysics

M. Dal Peraro

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Author profile →

3 papers

Recent·Most cited

Context-aware geometric deep learning for protein sequence design

L. Krapp, F. Meireles, L. Abriata, M. Dal Peraro

This paper introduces a geometric transformer model that predicts protein sequences from backbone scaffolds while considering molecular environment restraints.

Nature Communications · Jul 25, 2024Peer-reviewedBiochemistry

Deep learning-assisted single-molecule detection of protein post-translational modifications with a biological nanopore

C. Cao, P. Magalhaes, L. Krapp, J. Bada Juarez, S. Mayer, V. Rukes, A. Chiki, H. Lashuel, M. Dal Peraro

This study uses a biological nanopore and deep learning to detect and distinguish single and multiple PTMs on -synuclein peptides at picomolar concentrations.

bioRxiv · Sep 8, 2023Biophysics

Investigating crosstalk among PTMs provides novel insight into the structural basis underlying the differential effects of Nt17 PTMs on mutant Httex1 aggregation

A. Chiki, Z. Zhang, K. Rajasekhar, L. A. Abriata, I. Rostami, L. Krapp, D. Boudeffa, M. Dal Peraro, H. A. Lashuel

This study investigates how PTMs in Nt17 of mutant Httex1 affect aggregation, showing that oxM8 delays aggregation and that combinations with AcK6 inhibit fibrillization, with structural insights from spectroscopy and simulations.

bioRxiv · Feb 21, 2021Biophysics