Author

I. Testa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 6 Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:imaging· 4 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Approach:microscopy & imaging analysis· 3 Assay:fluorescence / live-cell microscopy· 2 Approach:Bayesian inference· 1 Organism:C. elegans· 1 Approach:deep learning· 1

Frequent Co-Authors

J. Alvelid· 3 shared A. Boden· 2 shared F. Pennacchietti· 2 shared G. Coceano· 2 shared L. Delemotte· 2 shared L. Rems· 2 shared A. H. Gynna· 1 shared F. D. Schramm· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersBiophysics

J. Alvelid

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Event-triggered STED imaging

J. Alvelid, M. Damenti, I. Testa

This paper introduces event-triggered STED imaging to capture high-resolution images of synaptic proteins during calcium sensing with improved temporal and spatial resolution.

bioRxiv · Oct 26, 2021Biophysics

Identification of electroporation sites in the complex lipid organization of the plasma membrane

L. Rems, X. Tang, F. Zhao, S. Perez-Conesa, I. Testa, L. Delemotte

This study identifies electroporation sites in the plasma membrane by combining simulations, machine learning, and Bayesian analysis, showing pores form in lipid domains with high polyunsaturated lipid density and depend on mechanical properties and electric field polarity.

bioRxiv · Oct 16, 2021Biophysics

Live cell imaging reveals that RecA finds homologous DNA by reduced dimensionality search

J. Wiktor, A. H. Gynna, P. Leroy, J. Larsson, G. Coceano, I. Testa, J. Elf

The paper uses live cell imaging to show that RecA filaments in E. coli find homologous DNA through a two-dimensional search mechanism, completing DSB repair within 15 minutes.

bioRxiv · Feb 13, 2020 · PreprintMicrobiology

Three dimensional parallelized RESOLFT nanoscopy for volumetric live cell imaging

A. Boden, F. Pennacchietti, I. Testa

This paper introduces a 3D parallelized RESOLFT nanoscopy method for live cell imaging, achieving sub-100 nm resolution with minimal illumination.

bioRxiv · Jan 9, 2020 · PreprintBiophysics

Pulsed electric fields create pores in the voltage sensors of voltage-gated ion channels

L. Rems, M. Kasimova, I. Testa, L. Delemotte

This study uses molecular dynamics simulations to show that pulsed electric fields create pores in voltage-sensor domains of voltage-gated ion channels, leading to dysfunction and altered ionic currents.

bioRxiv · Nov 11, 2019Biophysics

Tiled STED Imaging of Extended Sample Regions

J. Alvelid, I. Testa

This paper demonstrates automated STED nanoscopy for extended sample regions up to 0.5 x 0.5 mm2 with uniform resolution and feedback for focus maintenance.

bioRxiv · Oct 1, 2019Biophysics

Growth-driven displacement of protein aggregates along the cell length ensures partitioning to both daughter cells in Caulobacter crescentus

F. D. Schramm, K. Schroeder, J. Alvelid, I. Testa, K. Jonas

The paper studies protein aggregate inheritance in Caulobacter crescentus and finds that aggregates are symmetrically partitioned between daughter cells during division.

bioRxiv · Oct 5, 2018Microbiology

Enhanced photon collection enables four dimensional fluorescence nanoscopy of living systems

L. Masullo, A. Boden, F. Pennacchietti, G. Coceano, M. Ratz, I. Testa

The paper introduces MoNaLISA, a nanoscope that enables 4D fluorescence nanoscopy of living systems with enhanced photon collection, achieving sub-100 nm resolution at low light intensities.

bioRxiv · Jan 17, 2018Biophysics