Author

I. W. McNae

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Biophysics· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

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C. Georgiou· 1 shared H. Ioannidis· 1 shared J. Michel· 1 shared M. A. Wear· 1 shared M. D. Walkinshaw· 1 shared

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2017-2017 · peak 1/yr

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1 shared paperBiophysics

C. Georgiou

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1 paper

Recent·Most cited

BiophysicsbioRxivJun 15, 2017

Pushing The Limits Of Detection Of Weak Binding Using Fragment Based Drug Discovery: Identification Of New Cyclophilin Binders

C. Georgiou, I. W. McNae, M. A. Wear…·M. D. Walkinshaw

This paper identifies novel cyclophilin binders using fragment-based drug discovery and combines X-ray diffraction, SPR, and MD simulations to better characterize weak binding events.

DOI 10.1016/j.jmb.2017.06.016

protein structureexperimental assay

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