Author

I. Weinhauser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

G. Huls· 3 shared J. J. Schuringa· 3 shared D. A. Pereira-Martins· 2 shared E. Rego· 2 shared J. Hilberink· 2 shared A. Diepstra· 1 shared A. Lucena-Araujo· 1 shared A. M. de Leal· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCancer Biology

G. Huls

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Killing the enemy or making it your ally? The effects of thiostrepton on tumor associated macrophages

D. A. Pereira-Martins, J. Hilberink, I. Weinhauser, E. Rego, G. Huls, J. J. Schuringa

The paper examines how thiostrepton affects tumor-associated macrophages, exploring its potential to shift their polarization from M2 to M1.

bioRxiv · Mar 23, 2023 · PreprintCancer Biology

The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy

K. Lima, D. A. Pereira-Martins, L. B. L. de Miranda, J. L. Coelho-Silva, G. d. S. Leandro, I. Weinhauser, R. d. C. Cavaglieri, A. M. de Leal, W. F. da Silva, A. P. A. d. L. Lange, E. D. R. P. Velloso, E. Griessinger, J. R. Hilberink, G. Huls, J. J. Schuringa, , J. A. Machado-Neto

This study shows that THZ-P1-2, a PIP4K2 inhibitor, kills leukemia cells by disrupting mitochondrial homeostasis and autophagy, with minimal effects on healthy cells.

bioRxiv · Aug 20, 2022Pharmacology & Toxicology

M2-polarized macrophages control LSC fate by enhancing stemness, homing, immune evasion and metabolic reprogramming

I. Weinhauser, D. Pereira-Martins, L. Almeida, J. Hilberink, C. Ortiz, D. Silveira, L. Quek, C. Araujo, T. Bianco, A. Lucena-Araujo, N. Visser, S. Hogeling, A. Diepstra, E. Ammatuna, G. Huls, , J. J. Schuringa

The paper shows M2-polarized macrophages promote leukemia stem cell survival by enhancing stemness, homing, immune evasion, and metabolic reprogramming.

bioRxiv · May 6, 2022Cancer Biology