Author

Ignacio Fernández

Centre National de la Recherche Scientifique

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

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Ahmed HaouziD· 1 shared Atousa Arbabian· 1 shared Catherine BlanciD· 1 shared Eduard BaqueroiD· 1 shared Felix Augusto ReyiD· 1 shared Julian BuchrieseriD· 1 shared Nell SaundersiD· 1 shared Olivier SchwartziD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiochemistry

Ahmed HaouzORCID

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1 paper

Recent·Most cited

BiochemistryCellPeer-reviewedJul 3, 2024

Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus

Ignacio Fernández, Nell Saunders, S. Duquerroy…·Felix Augusto Rey

This study determines the structure of HKU1-CoV receptor binding domain in complex with TMPRSS2, identifying key residues for host tropism and revealing the structural basis of TMPRSS2 activation.

36 citationstop 1%

humanstructural biology

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