Cancer BiologybioRxivPreprint
Regulation of KRAS4A/B splicing in cancer stem cells by the RBM39 splicing complex.
Wei-Ching Chen, Minh D. To, Peter M.K. Westcott…·Allan Balmain
This study identifies KRAS4A and KRAS4B splice isoforms with distinct expression patterns in cancer stem cells and shows that targeting KRAS4A splicing is a potential therapeutic strategy in KRAS mutant tumors.
DOI 10.1101/646125