MicrobiologyiSciencePeer-reviewed
The L,D-transpeptidation pathway is inhibited by antibiotics of the β-lactam class in Clostridioides difficile
Ana M. Oliveira Paiva, Pascal Courtin, Glenn Charpentier…·Peltier Johann
This study shows that cephalosporin resistance in C. difficile is due to inhibition of D,D-carboxypeptidases, not L,D-transpeptidases, and highlights the plasticity of PG biosynthesis.
6 citations