Indira Wu

This study uses LoopSeq, a synthetic long read sequencing method, to analyze isoform changes in colon cancer and identifies novel gene fusions and isoform-specific SNVs.

The paper introduces LoopSeq, a synthetic long-read sequencing method using short-read platforms to reconstruct full-length transcripts with high accuracy and identifies novel splice variants in human tissues.

This paper introduces Linked-Reads as a method to comprehensively analyze genome variation, showing it can detect both small and large variants and reconstruct haplotypes more effectively than short-read sequencing.