Cancer BiologyTranslational OncologyPeer-reviewed
Chitinase 3-like-1 (CHI3L1) in the Pathogenesis of Epidermal Growth Factor Receptor Mutant Non-Small Cell Lung Cancer
Suchitra Kamle, Bing Ma, Gail Schor…·Jack Angel Elias
This study shows CHI3L1 is induced by EGFR activation in NSCLC and promotes EGFR signaling, with anti-CHI3L1 antibodies reversing TKI resistance and inhibiting metastasis.
8 citations