BiochemistrybioRxivPreprint
A previously-unrecognized motif of transcription factor RYBP, hotspot of cancer-related mutations, is essential for the integrity of Polycomb repressive complex 1
Catarina S. Silva, Laura Mariño, Irene Garcia Ferrer…·Marco Marcia
This study identifies a critical RYBP motif in vPRC1 essential for complex stability and linked to cancer mutations, using AlphaFold2 and NMR.