Author

Ishak D. Irwan

Duke Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Bryan R. CulleniD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

1 paper

Recent·Most cited

Molecular BiologyJournal of VirologyPeer-reviewedApr 19, 2021

Tax induces the recruitment of NF-kB to unintegrated HIV-1 DNA to rescue viral gene expression and replication

Ishak D. Irwan, Bryan R. Cullen

The paper shows Tax rescues HIV-1 replication by recruiting NF-kB to unintegrated viral DNA, enabling transcription and epigenetic changes, and describes effective IN-lentiviral vectors.

14 citations

humanDNA methylation

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