Cancer BiologybioRxivPreprint
Interferon-independent STING enforces epithelial genome-integrity checkpoint to restrain tumor evolution
Xiang Hang, Martina Macino, Clemens Woitaske-Proske…·Konrad Aden
This study shows that STING acts as a genome-integrity checkpoint in epithelial cells, independent of interferon, and its loss leads to chromosomal instability and tumor development.
DOI 10.64898/2026.02.17.706442