Author

J. A. Kuhn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

S. Dumont· 2 shared

Activity by Year

2017-2018 · peak 1/yr

2 papers

Recent·Most cited

Cell BiologybioRxivNov 6, 2018

Mammalian kinetochores count attached microtubules in a sensitive and switch-like manner to control cell cycle progression

J. A. Kuhn, S. Dumont

The paper investigates how mammalian kinetochores detect microtubule attachments to control the SAC, finding that they respond specifically and switch-like to microtubule binding.

DOI 10.1083/jcb.201902105

experimental assaycell signaling & trafficking

𝕏 PostBluesky

Cell BiologybioRxivFeb 3, 2017

Spindle assembly checkpoint satisfaction occurs through end-on but not lateral kinetochore-microtubule interactions under tension

J. A. Kuhn, S. Dumont

The paper shows that SAC satisfaction in mitosis depends on end-on kinetochore-microtubule attachments generating tension, not lateral attachments, which can maintain tension but do not trigger SAC silencing.

DOI 10.1083/jcb.201611104

humanexperimental assay

𝕏 PostBluesky