Author

J. Baer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 6 Plant Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Organism:Arabidopsis· 2 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

A. S. Zinkernagel· 6 shared C. Vulin· 3 shared S. D. Brugger· 3 shared A. Tarnutzer· 2 shared J. C. Walker· 2 shared M. Huemer· 2 shared R. D. Kouyos· 2 shared S. Mairpady Shambat· 2 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

6 shared papersMicrobiology

A. S. Zinkernagel

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Single-cell approach dissecting agr quorum sensing dynamics in Staphylococcus aureus

J. Baer, S. G. V. Charlton, A. Tarnutzer, G. S. Ugolini, E. Secchi, A. S. Zinkernagel

The paper uses single-cell techniques to study agr quorum sensing dynamics in Staphylococcus aureus, revealing differences in AIP sensitivity and community interaction patterns across agr-types.

bioRxiv · Feb 27, 2024 · PreprintMicrobiology

C-di-AMP levels modulate Staphylococcus aureus cell wall thickness as well as virulence and contribute to antibiotic resistance and tolerance

V. Dengler Haunreiter, A. Tarnutzer, J. Baer, M. von Matt, S. Hertegonne, F. Andreoni, C. Vulin, L. Künzi, C. Menzi, P. Kiefer, P. Christen, J. A. Vorholt, A. S. Zinkernagel

This study shows that high c-di-AMP levels in Staphylococcus aureus increase cell wall thickness and antibiotic resistance, while reducing cell size and antioxidant production.

bioRxiv · Apr 18, 2023Microbiology

Arabidopsis uses a molecular grounding mechanism and a biophysical circuit breaker to limit floral abscission signaling

I. W. Taylor, O. R. Patharkar, C.-W. Hsu, J. Baer, M. Mijar, C. E. Niederhuth, U. Ohler, P. N. Benfey, J. C. Walker

This study identifies MKP1 as a negative regulator of the HAE/HSL2 abscission pathway in Arabidopsis and shows how IDA expression patterns act as a biophysical circuit breaker to terminate signaling.

bioRxiv · Jul 14, 2022Plant Biology

Rapid detection of Staphylococcus aureus and Streptococcus pneumoniae by real-time analysis of volatile metabolites

A. G. Mejia, K. Arnold, J. Baer, K. D. Sing, T. C. Scheier, S. D. Brugger, A. S. Zinkernagel, P. Sinues

This paper evaluates SESI-HRMS for rapid detection of S. aureus and S. pneumoniae by analyzing VOCs, showing faster and more sensitive identification than conventional methods.

bioRxiv · Mar 16, 2022Microbiology

Reducing structural non-identifiabilities in upstream bioprocess models using profile-likelihood

H. Babel, O. Omar, A. J. Paul, J. Baer

This study applies profile likelihood to assess parameter identifiability in an upstream bioprocess model, showing that adding data reduces non-identifiability and enables structural model improvements.

bioRxiv · Feb 17, 2022 · PreprintBioengineering

Quantification of within patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations

J. Baer, M. Boumasmoud, S. Mairpady Shambat, C. Vulin, M. Huemer, T. A. Schweizer, A. Gómez Mejia, N. Eberhard, Y. Achermann, P. O. Zingg, C. A. Mestres, S. D. Brugger, R. A. Schüpbach, R. D. Kouyos, B. Hasse, A. S. Zinkernagel

This study quantifies phenotypic heterogeneity in Staphylococcus aureus from patient samples to assess persisters, finding that rifampicin treatment correlates with increased growth delays.

bioRxiv · Jul 27, 2021Microbiology

Ser/Thr phospho-regulation by PknB and Stp mediates bacterial quiescence and antibiotic persistence in Staphylococcus aureus

M. Huemer, S. Mairpady Shambat, S. Pereira, L. Van Gestel, J. Bergada-Pijuan, A. Gomez Mejia, C.-C. Chang, C. Vulin, J. Baer, J. Dworkin, A. S. Zinkernagel

bioRxiv · May 6, 2021Microbiology

Quantifying variation in bacterial reproductive fitness with and without antimicrobial resistance: a high-throughput method

P. M. Frey, J. Baer, J. Bergada Pijuan, C. Lawless, P. K. Bühler, R. D. Kouyos, K. P. Lemon, A. S. Zinkernagel, S. D. Brugger

This paper introduces baQFA, a low-cost high-throughput method to quantify bacterial reproductive fitness with and without antimicrobial resistance using time-lapse imaging and Gompertz modeling.

bioRxiv · May 13, 2020Microbiology

Hypermorphic SERK1 mutations function via a SOBIR1 pathway to activate floral abscission signaling

I. Taylor, J. Baer, R. Calcutt, J. C. Walker

The paper identifies hypermorphic SERK1 mutations that activate floral abscission signaling independently of HAE/HSL2 by interacting with SOBIR1.

bioRxiv · Oct 26, 2018Plant Biology