Intracellular Vesicle Entrapment of Nanobubble Ultrasound Contrast Agents Targeted to PSMA Promotes Prolonged Enhancement and Stability In Vivo and In Vitro
R. Perera, E. Abenojar, P. Nittayacharn, X. Wang, G. Ramamurthy, P. Peiris, I. Bederman, J. Basilion, A. Exner
This study investigates how PSMA-targeted nanobubbles enhance ultrasound imaging in prostate tumors by being internalized and retained in intracellular vesicles, leading to prolonged signal and stability.
bioRxiv · May 11, 2021Cancer Biology