Author
J. Beaulieu
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2017-2024 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 8 mutual co-author links8 papers
Recent·Most cited
Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells
F.-M. Cloarec-Ung, J. Beaulieu, A. Suthananthan, B. Lehnertz, G. Sauvageau, H. M. Sheppard, D. J. Knapp
This study achieves near-perfect on-target gene editing in human hematopoietic stem and progenitor cells with high efficiency and minimal off-target effects.
bioRxiv · May 26, 2023Bioengineering
Long-term responses of life-history strategies to climatic variability in flowering plants
J. D. Boyko, E. R. Hagen, J. Beaulieu, T. Vasconcelos
This study examines how climatic variability influences life-history strategies in flowering plants, finding that temperature, especially maximum temperature of the warmest month, is the key factor, and that perennials evolve climatic niches faster than annuals.
bioRxiv · Oct 19, 2022 · PreprintEvolutionary Biology
Generalized Hidden Markov Models for Phylogenetic Comparative Datasets
The paper generalizes hidden Markov models for phylogenetic comparative datasets, showing improved ancestral state reconstruction and demonstrating their application to flower character evolution.
bioRxiv · Jul 18, 2020Evolutionary Biology
A spatially-explicit model of stabilizing selection for improving phylogenetic inference
J. Beaulieu, B. O'Meara, M. Gilchrist
This paper introduces SelON, a spatially-explicit model of stabilizing selection for phylogenetic inference, showing improved model fit and supporting turtles as sister to lepidosaurs.
bioRxiv · May 12, 2020Evolutionary Biology
Population Genetics Based Phylogenetics Under Stabilizing Selection for an Optimal Amino Acid Sequence: A Nested Modeling Approach
J. Beaulieu, B. O'Meara, R. Zaretzki, C. Landerer, J. Chai, M. A. Gilchrist
The paper introduces SelAC, a phylogenetic model that improves tree inference by incorporating stabilizing selection and protein synthesis rates, showing better fit than existing models on yeast data.
bioRxiv · Oct 9, 2018Evolutionary Biology
Hidden state models improve the adequacy of state-dependent diversification approaches using empirical trees, including biogeographical models
D. Caetano, B. O'Meara, J. Beaulieu
This paper introduces GeoHiSSE, an extension of hidden Markov models to geographic state-dependent speciation and extinction models, showing improved detection of diversification shifts.
bioRxiv · Apr 17, 2018Evolutionary Biology
Insights into global planktonic diatom diversity:Comparisons between phylogenetically meaningful unitsthat account for time
T. Nakov, J. Beaulieu, A. Alverson
The paper shows that genus-level analyses of diatom diversity are confounded by varying speciation/extinction rates and phylogenetic nesting, emphasizing the need for phylogenetic approaches.
bioRxiv · Jul 24, 2017Evolutionary Biology