Author

C. Landerer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 4 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:Bayesian inference· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Toth-Petroczy· 3 shared M. A. Gilchrist· 2 shared R. Zaretzki· 2 shared A. A. Hyman· 1 shared A. Giner· 1 shared B. C. O'Meara· 1 shared B. O'Meara· 1 shared C. Jegers· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersBiochemistry

A. Toth-Petroczy

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Author profile →

5 papers

Recent·Most cited

A conserved and tunable mechanism for the temperature-controlled condensation of the translation factor Ded1p

C. Jegers, T. M. Franzmann, J. Hübner, J. Schneider, C. Landerer, S. Wittmann, A. Toth-Petroczy, R. Sprangers, A. A. Hyman, S. Alberti

The paper investigates how Ded1p translation factors assemble into condensates in response to heat across fungi, identifying structural and amino acid determinants of temperature sensitivity.

bioRxiv · Oct 11, 2022 · PreprintBiochemistry

Evolutionary impact of codon specific translation errors at the proteome scale

A. Toth-Petroczy, C. Landerer, J. Poehls

The paper develops a computational pipeline to detect proteome-wide translation errors across organisms, revealing how codon choice affects error rates and showing the translation machinery's role in preventing deleterious errors.

bioRxiv · Oct 11, 2022Evolutionary Biology

The novel Rab5 effector FERRY links early endosomes with the translation machinery

J. S. Schuhmacher, S. tom Dieck, S. Christoforidis, C. Landerer, J. Davila Gallesio, L. Hersemann, S. Seifert, R. Schaefer, A. Giner, A. Toth-Petroczy, Y. Kalaidzidis, K. E. Bohnsack, M. T. Bohnsack, E. M. Schuman, M. Zerial

This study identifies FERRY as a Rab5 effector that localizes mRNAs and ribosomes to early endosomes, impacting mRNA distribution and causing brain damage when disrupted.

bioRxiv · Jun 20, 2021 · PreprintCell Biology

Unlocking a signal of introgression from codons in Lachancea kluyveri using a mutation-selectino model

C. Landerer, B. C. O'Meara, R. Zaretzki, M. A. Gilchrist

The paper uses a mutation-selection model to analyze codon usage differences between endogenous and introgressed genes in Lachancea kluyveri, revealing distinct mutation biases and improving predictions of protein synthesis rates.

bioRxiv · Jun 5, 2020Evolutionary Biology

Population Genetics Based Phylogenetics Under Stabilizing Selection for an Optimal Amino Acid Sequence: A Nested Modeling Approach

J. Beaulieu, B. O'Meara, R. Zaretzki, C. Landerer, J. Chai, M. A. Gilchrist

The paper introduces SelAC, a phylogenetic model that improves tree inference by incorporating stabilizing selection and protein synthesis rates, showing better fit than existing models on yeast data.

bioRxiv · Oct 9, 2018Evolutionary Biology