Author

J. C. Trefry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:non-human primate· 3 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

F. Nasar· 2 shared M. L. Pitt· 2 shared S. Bavari· 2 shared S. E. Wollen-Roberts· 2 shared A. E. Kimmel· 1 shared A. M. Babka· 1 shared A. N. Honko· 1 shared A. P. Cardile· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

F. Nasar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Single-shot ChAd3 Vaccine Provides Protection from Intramuscular and Aerosol Sudan Virus Exposure

A. N. Honko, R. Hunegnaw, J. I. Moliva, A. Ploquin, C. N. M. Dulan, T. Murray, D. Carr, K. E. Foulds, J. B. Geisbert, T. W. Geisbert, J. C. Johnson, S. E. Wollen-Roberts, J. C. Trefry, D. A. Stanley, N. J. Sullivan

A single dose of ChAd3-SUDV vaccine protected macaques from lethal SUDV challenge via parenteral and aerosol routes.

bioRxiv · Feb 7, 2024 · PreprintImmunology

Eastern Equine Encephalitis Virus Rapidly Infects and Disseminates in the Brain and Spinal Cord of Infected Cynomolgus Macaques Following Aerosol Challenge

J. A. Williams, S. Y. Long, X. Zeng, K. Kuehl, A. M. Babka, N. M. Davis, J. Liu, J. C. Trefry, S. Daye, P. R. Facemire, P. L. Iversen, S. Bavari, M. L. Pitt, F. Nasar

This study investigates EEEV pathogenesis in cynomolgus macaques following aerosol challenge, finding that the virus replicates in the olfactory bulb and spreads via axonal transport, causing neuronal dysfunction rather than death.

bioRxiv · Dec 21, 2020Microbiology

The Utilization of Advance Telemetry to Investigate Important Physiological Parameters Including Electroencephalography in Cynomolgus Macaques Following Aerosol Challenge with Eastern Equine Encephalitis Virus

J. C. Trefry, F. D. Rossi, M. Accardi, B. Dorsey, T. R. Sprague, S. E. Wollen-Roberts, J. D. Shamblin, A. E. Kimmel, P. J. Glass, L. Miller, A. P. Cardile, D. R. Smith, S. Bavari, S. Authier, W. D. Pratt, , F. Nasar

This study uses advanced telemetry in cynomolgus macaques to monitor physiological parameters after EEEV aerosol challenge, revealing severe alterations in cardiac and neurological functions leading to euthanasia.

bioRxiv · Dec 21, 2020Microbiology