Loss of MGA mediated Polycomb repression promotes tumor progression and invasiveness
H. Mathsyaraja, J. Catchpole, E. Eastwood, E. Babaeva, M. J. Geuenich, P.-F. Cheng, B. Freie, J. L. Ayers, M. Yu, N. Wu, K. R. Poudel, A. Koehne, W. Grady, A. M. Houghton, Y. Shiio, , R. N. Eisenman
This study shows that loss of MGA promotes tumor growth and invasiveness by de-repressing Polycomb targets in lung and colon cancers.
eLife · Jul 8, 2021Peer-reviewedCancer Biology