This study shows that mitochondrial calcium signaling regulates branched-chain amino acid catabolism and the urea cycle in fibrolamellar carcinoma through transcriptional control of metabolic genes.

bioRxiv · May 27, 2024Cell Biology

AML ImmunoPET: 64Cu-DOTA-anti-CD33 PET-CT imaging of AML in Xenograft mouse model

S. S. Madabushi, J. L. Brooks, D. Zuro, B. Kumar, J. Sanchez, L. Echavarria Parra, M. Orellana, P. Vishwasrao, I. Nair, J. Chea, K. Poku, N. Bowles, A. Miller, T. Ebner, J. Molnar, , S. K. Hui

This paper develops a 64Cu-DOTA-anti-CD33 PET-CT imaging method for detecting AML in xenograft mouse models with high sensitivity and specificity, showing spatial heterogeneity in disease distribution.

bioRxiv · May 10, 2019 · PreprintCancer Biology

Seasonal changes in diet and toxicity in the Climbing Mantella frog (Mantella laevigata)

N. A. Moskowitz, A. B. Roland, E. K. Fischer, N. Ranaivorazo, C. Vidoudez, M. T. Aguilar, S. M. Caldera, J. Chea, M. G. Cristus, J. P. Crowdis, B. DeMessie, C. R. Desjardins-Park, A. H. Effenberger, F. Flores, M. Giles, , L. A. O'Connell

This study examines how seasonal environmental changes affect the diet and toxin profiles of Climbing Mantella frogs, finding seasonal differences in diet composition and toxin abundance.

bioRxiv · Oct 13, 2018Ecology