Author

G. E. Atilla-Gokcumen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

O. Gokcumen· 3 shared M. Saitou· 2 shared A. J. Pradhan· 1 shared A. Millner· 1 shared C. Lee· 1 shared D. Lizardo· 1 shared D. Lu· 1 shared F. Wu· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCell Biology

O. Gokcumen

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Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 22, 2022

SREBP1 activation contributes to fatty acid accumulations in necroptosis

D. Lu, L. R. Parisi, O. Gokcumen, G. E. Atilla-Gokcumen

This study shows SREBP1 activation leads to VLCFA accumulation, which worsens necroptosis by increasing membrane permeabilization.

DOI 10.1101/2022.08.22.504843

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

Evolutionary BiologybioRxivMar 1, 2021

Sex-specific phenotypic effects and evolutionary history of an ancient polymorphic deletion of the human growth hormone receptor

M. Saitou, S. Resendez, A. J. Pradhan…·O. Gokcumen

This study investigates the evolutionary history and phenotypic effects of the GHRd3 deletion, finding sex- and environment-dependent impacts on growth and metabolism.

DOI 10.1126/sciadv.abi4476

𝕏 PostBluesky

Cell BiologybioRxivApr 3, 2018

An evolutionary transcriptomics approach links CD36 to membrane remodeling in replicative senescence

M. Saitou, D. Lizardo, R. Taskent…·O. Gokcumen

This study identifies CD36 as a key gene upregulated in senescent cells, linking it to membrane remodeling through lipid metabolism and senescence-like phenotypes.

DOI 10.1039/c8mo00099a

humanbulk RNA-seq

𝕏 PostBluesky