A. Miller

Indistinct changes in the mammal fauna between 1986-2017 at Judbarra-Gregory National Park, Northern Territory

The paper examines mammal fauna changes in Judbarra-Gregory National Park from 1986-2017, finding no substantial changes in composition or abundance, but noting some species trends and correlations with fire and vegetation metrics.

Accelerated phenology fails to buffer fitness loss from delayed rain onset in a clade of wildflowers

The study examines how delayed rain onset affects germination timing and fitness in ten wildflower species, finding species-specific responses to climate change.

A protective role for B-1 cells and oxidation-specific epitope IgM in lung fibrosis

This study shows B-1 cells and IgMOSE reduce lung fibrosis by modulating CXCR4 and Id3, with sIgM-/- mice showing increased mortality from bleomycin injury.

Terroir and rootstock effects on leaf shape in California Central Valley vineyards

The paper examines how terroir and rootstock influence leaf shape in grapevines, identifying a specific morphological feature affected by these factors.

Nanoscale profiling of evolving intermolecular interactions in ageing FUS condensates

This study characterizes the aging behavior of FUS condensates using microfluidic technology and surface-based techniques, revealing phase transitions and structural changes associated with material properties.

The effect of clinically relevant beta-lactam, aminoglycoside, and quinolone antibiotics on bacterial extracellular vesicle release from E. coli

This study examines how clinically relevant antibiotics affect extracellular vesicle release from E. coli, finding that beta-lactams increase release while quinolones and aminoglycosides decrease it.

Optimising a self-assembling peptide hydrogel as a Matrigel alternative for 3-dimensional mammary epithelial cell culture

This study optimizes self-assembling peptide hydrogels to better support mammary epithelial cell organoid formation compared to Matrigel.

Germination responses to changing rainfall timing reveal potential climate vulnerability in a clade of wildflowers

This study examines how changes in rainfall timing affect germination in 11 wildflower species, finding that later rains and cooler temperatures reduce germination rates and fractions, with phylogenetic constraints and climate change impacts observed.

Dynamical modeling reveals RNA decay mediates the effect of matrix stiffness on aged muscle stem cell fate

This study shows that matrix stiffness affects aged muscle stem cell self-renewal through RNA decay dynamics, which can be modulated by young matrix environments.

Mass cytometry identifies dysregulation of circulating and cutaneous immune cells in patients with hidradenitis suppurativa

This study identifies immune cell dysregulation in hidradenitis suppurativa using mass cytometry and RNA-seq, finding increased CD38 expression in monocytes and suggesting CD38 as a therapeutic target.

Reticulocytes in donor RBC units enhance RBC alloimmunization

This study shows that reticulocytes in donor RBC units increase alloimmunization rates in mice by enhancing alloantibody levels and proinflammatory responses.

Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model.

Grapevine leaf size influences vine canopy temperature

The paper examines the relationship between grapevine leaf size and canopy temperature, finding that larger leaves are associated with cooler canopy temperatures.

An Epitope-Focused Trypanosome-Derived Vaccine Platform Elicits High-Affinity Antibodies and Immunity Against Fentanyl Effects

This paper develops a trypanosome-derived vaccine platform (VAST) that elicits high-affinity antibodies against fentanyl, demonstrating protective immunity through single-cell RNAseq and crystallography.

Temporal and environmental factors interact with rootstock genotype to shape leaf elemental composition in grafted grapevines

This study shows rootstock genotype interacts with time and environment to influence leaf elemental composition in grafted grapevines.

A unique Thy-1-negative immuno-fibroblast population emerges as a key determinant of fibrotic outcomes to biomaterials

The paper identifies a Thy-1-negative fibroblast subpopulation that drives fibrosis in response to biomaterials using single-cell RNA sequencing.

Shared hotspot mutations in spontaneously arising cancers position dog as an unparalleled comparative model for precision therapeutics

This study identifies shared hotspot mutations in canine and human cancers, highlighting dogs as a valuable model for precision cancer therapeutics.

The genetic basis of tail-loss evolution in humans and apes

This paper identifies an Alu element insertion in the TBXT gene as the genetic mechanism driving tail-loss evolution in hominoids, showing it causes alternative splicing and tail absence in mice.

Inhibition of cancer cells in culture. The effects of treatment with ketone bodies and/or rapamycin treatment

This study shows that ketone bodies and rapamycin inhibit cancer cell proliferation in culture, with additive effects, suggesting potential for reducing drug doses when combined.

Host poly(A) polymerases PAPD5 and PAPD7 provide two layers of protection that ensure the integrity and stability of hepatitis B virus RNA

This study investigates how PAPD5 and PAPD7 stabilize HBV RNA and shows that PAPD5 is dominant in protecting the poly(A) tail, while PAPD7 acts as a backup mechanism.

Extracellular Matrix Remodeling Associated With Bleomycin-Induced Lung Injury Supports Pericyte-To-Myofibroblast Transition

This paper investigates how pericytes transition into myofibroblasts during lung injury, showing that fibronectin and vβ3 integrin engagement drive this process and may be targeted to reduce fibrosis.

Orally Bioavailable Endochin-like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts

This study develops an orally bioavailable prodrug of ELQ-316 that enhances its plasma concentrations and efficacy against Toxoplasma gondii infection.

Single Chlamydomonas reinhardi (C. reinhardtii) cell separation from bacterial cells and auto-fluorescence tracking with a nano-sieve device

This paper develops a nano-sieve device for separating microalgae from bacteria and tracking single cells via auto-fluorescence.

Comparative therapeutic potential of ALX-0171 and palivizumab against RSV clinical isolate infection of well-differentiated primary pediatric bronchial epithelial cell cultures

This study compares the therapeutic efficacy of ALX-0171 and palivizumab against RSV infection in a human bronchial epithelial cell model, showing ALX-0171 is more potent at neutralizing virus but less effective at reducing viral genomic copies.

Probing the Subcellular Distribution of Phosphatidylinositol Reveals a Surprising Lack at the Plasma Membrane

The study maps the subcellular distribution of phosphatidylinositol (PI) and finds it is largely absent from the plasma membrane, where it is mainly present as PI4P and PI(4,5)P2.

An ethnobotanical study of the genus Elymus

This study surveys ethnobotanical uses of the perennial grass genus Elymus and examines floret size variation in species with human uses.

Probabilistic Models of Larval Zebrafish Behavior: Structure on Many Scales

This study models larval zebrafish behavior using probabilistic frameworks to understand how hunger state and environmental factors influence action selection during exploration and hunting.

MinION Sequencing of colorectal cancer tumour microbiomes - a comparison with amplicon-based and RNA-Sequencing

This study compares MinION sequencing with RNA-Sequencing and 16S rRNA amplicon sequencing for microbiome analysis of colorectal cancer samples, finding MinION's long reads can compensate for low read counts and detect more taxa.

Characterizing grapevine (Vitis spp.) inflorescence architecture using X-ray imaging: implications for understanding cluster density

The paper uses X-ray imaging and computational methods to analyze grapevine inflorescence architecture across species, identifying traits linked to cluster density and phylogenetic patterns.

AML ImmunoPET: 64Cu-DOTA-anti-CD33 PET-CT imaging of AML in Xenograft mouse model

This paper develops a 64Cu-DOTA-anti-CD33 PET-CT imaging method for detecting AML in xenograft mouse models with high sensitivity and specificity, showing spatial heterogeneity in disease distribution.