J. Chicher

Identification of new proviral and antiviral factors through the study of the Dicer-2 interactome in vivo during viral infection in Drosophila melanogaster

DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection

This study identifies DDX5 as a pro-viral host factor for Sindbis virus infection, showing its interaction with viral RNA and capsid protein, and demonstrating that its depletion reduces viral replication.

Comparative proteomics uncovers low asparagine insertion in Plasmodium tRip-KO proteins.

The paper compares proteomic data from wild-type and tRip-KO P. berghei parasites, finding a bias toward low asparagine content in down-regulated proteins and proposing host tRNA involvement in parasite protein synthesis.

A NYN domain protein directly interacts with DCP1 and is required for phyllotactic pattern in Arabidopsis.

DNE1, a NYN domain protein interacts with DCP1 and, together with DCP2, specify phyllotactic patterns in Arabidopsis.

Human DICER helicase domain recruits PKR and modulates its antiviral activity

The paper shows that DICER's helicase domain recruits PKR and modulates its antiviral activity during alphavirus infection.

Proteomics-based determination of double stranded RNA interactome reveals known and new factors involved in Sindbis virus infection

This study identifies SFPQ as a new proviral factor involved in Sindbis virus infection by characterizing the dsRNA interactome using anti-dsRNA immunoprecipitation and mass spectrometry.