Organoid Polymer Functionality and Mode of Klebsiella Pneumoniae Membrane Antigen Presentation Regulates Ex Vivo Germinal Center Epigenetics in Young and Aged B Cells
P. L. Graney, K. Lai, S. Post, I. Brito, J. Cyster, A. Singh
The paper develops PEG-organoids to study how polymer chemistry and antigen presentation affect germinal center-like B cell epigenetics in young and aged mice.
bioRxiv · Feb 16, 2020Immunology